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Motif ID: MEF2{A,B,C,D}.p2

Z-value: 2.385

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_79625538	3.260	NM_002469	MYF6	myogenic factor 6 (herculin)
chr5_+_155686333	3.246	NM_000337 NM_001128209 NM_172244	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr10_+_50177192	3.057	NM_001135196 NM_199459	C10orf71	chromosome 10 open reading frame 71
chr10_+_69539255	3.053	NM_032578	MYPN	myopalladin
chr2_-_190635566	2.984	NM_005259	MSTN	myostatin
chr10_-_75085754	2.960	NM_001114133	SYNPO2L	synaptopodin 2-like
chr3_-_39209075	2.953	NM_194293 NM_001198621	XIRP1	xin actin-binding repeat containing 1
chr2_+_88148413	2.814	NM_198274	SMYD1	SET and MYND domain containing 1
chr10_-_75080784	2.655	NM_024875	SYNPO2L	synaptopodin 2-like
chr8_+_67201684	2.623	NM_033058 NM_184085 NM_184086 NM_184087	TRIM55	tripartite motif containing 55
chr2_+_170074457	2.586	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr16_+_31132842	2.520	NM_001008274	TRIM72	tripartite motif containing 72
chr5_+_53787187	2.386	NM_006308	HSPB3	heat shock 27kDa protein 3
chr1_-_199657468	2.359	NM_003281	TNNI1	troponin I type 1 (skeletal, slow)
chr10_+_111755715	2.301	NM_019903	ADD3	adducin 3 (gamma)
chrX_-_21686079	2.115	NM_014332	SMPX	small muscle protein, X-linked
chr2_+_238712101	2.108	NM_198582	KLHL30	kelch-like 30 (Drosophila)
chr1_-_199613406	2.106		TNNT2	troponin T type 2 (cardiac)
chr4_+_169654742	2.050	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr22_+_24468168	2.034		MYO18B	myosin XVIIIB
chr1_-_199613427	2.027	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr7_+_93862137	1.926		COL1A2 PLAG1	collagen, type I, alpha 2 pleiomorphic adenoma gene 1
chr12_-_55931172	1.875	NM_145064	STAC3	SH3 and cysteine rich domain 3
chr22_+_24468110	1.835	NM_032608	MYO18B	myosin XVIIIB
chr1_-_151784889	1.799	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr16_+_14187965	1.712		MKL2	MKL/myocardin-like 2
chr11_-_85107569	1.691	NM_206929	SYTL2	synaptotagmin-like 2
chr3_+_8750485	1.580	NM_033337 NM_001234	CAV3	caveolin 3
chr17_+_42641712	1.476	NM_002476	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr2_-_210876560	1.472	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr18_-_3209986	1.412	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr2_-_105421661	1.412	NM_201557	FHL2	four and a half LIM domains 2
chr3_+_35658852	1.400	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr3_+_35696119	1.389	NM_001025068 NM_001025069	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr7_+_154943466	1.336	NM_001427	EN2	engrailed homeobox 2
chr1_+_144124547	1.336	NM_145277 NM_202004 NM_213652 NM_213653	HFE2	hemochromatosis type 2 (juvenile)
chr5_-_111119846	1.334	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr2_-_179623030	1.206	NM_173648	CCDC141	coiled-coil domain containing 141
chr7_+_18501876	1.170	NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr20_+_19903778	1.168		RIN2	Ras and Rab interactor 2
chrX_-_142549984	1.130	NM_001184750	SLITRK4	SLIT and NTRK-like family, member 4
chr18_-_3209846	1.118		MYOM1	myomesin 1, 185kDa
chr17_-_24491521	1.115		MYO18A	myosin XVIIIA
chr12_+_118100977	1.085	NM_014365	HSPB8	heat shock 22kDa protein 8
chr16_-_31347151	1.085	NM_005205	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr15_+_61676604	1.076	NM_203373	FBXL22	F-box and leucine-rich repeat protein 22
chr20_+_60558104	1.060	NM_178463	C20orf166	chromosome 20 open reading frame 166
chr14_+_23670514	1.059	NM_203402	FITM1	fat storage-inducing transmembrane protein 1
chr3_-_115825742	1.035	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr12_-_21985433	1.034		ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_-_10500189	1.032	NM_002470	MYH3	myosin, heavy chain 3, skeletal muscle, embryonic
chrX_+_152699616	1.022	NM_001170760 NM_001170761 NM_014370	SRPK3	SRSF protein kinase 3
chr1_-_154727014	1.021		MEF2D	myocyte enhancer factor 2D
chr19_+_23091616	1.021		ZNF730	zinc finger protein 730
chr17_+_42641426	1.016	NM_001002841	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr8_-_72431274	1.007	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr7_-_113346284	0.956	NM_002711	PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_-_76259976	0.952	NM_015687	FILIP1	filamin A interacting protein 1
chr6_-_130224108	0.950	NM_001010876	C6orf191	chromosome 6 open reading frame 191
chr11_-_62213577	0.934		LRRN4CL	LRRN4 C-terminal like
chr2_-_162808123	0.931	NM_004460	FAP	fibroblast activation protein, alpha
chr3_-_102194938	0.928	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr1_-_16217025	0.905		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr10_+_88418243	0.880	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr1_+_201364050	0.872		ADORA1	adenosine A1 receptor
chr11_-_19180092	0.868	NM_001127656 NM_003476	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr7_+_18502342	0.861	NM_058176 NM_178425	HDAC9	histone deacetylase 9
chr3_+_129117007	0.859		KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr12_-_109842736	0.848	NM_000432	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr9_+_115367122	0.848	NM_134427	RGS3	regulator of G-protein signaling 3
chr4_-_177427252	0.842	NM_080874	ASB5	ankyrin repeat and SOCS box containing 5
chr6_+_42896771	0.832	NM_015349	KIAA0240	KIAA0240
chr1_+_154478574	0.831	NM_199173	BGLAP	bone gamma-carboxyglutamate (gla) protein
chr6_-_139654807	0.825	NM_153235	TXLNB	taxilin beta
chr1_-_26266571	0.824	NM_032588	TRIM63	tripartite motif containing 63
chr10_-_69095362	0.823	NM_001127384	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr1_+_242283129	0.815	NM_006352	ZNF238	zinc finger protein 238
chr15_-_68781662	0.814	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_+_30917939	0.813	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr17_-_77474597	0.807	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr2_+_233099113	0.793	NM_000751	CHRND	cholinergic receptor, nicotinic, delta
chr1_-_100416358	0.785	NM_144620	LRRC39	leucine rich repeat containing 39
chr1_-_116112684	0.783		CASQ2	calsequestrin 2 (cardiac muscle)
chrX_-_138114100	0.771		FGF13	fibroblast growth factor 13
chrX_-_77801480	0.765	NM_152694	ZCCHC5	zinc finger, CCHC domain containing 5
chr1_-_202595666	0.761	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr3_+_139550368	0.745		MRAS	muscle RAS oncogene homolog
chr10_+_80569464	0.744		ZMIZ1	zinc finger, MIZ-type containing 1
chr5_-_142057692	0.742	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr2_+_149603226	0.728	NM_177964	LYPD6B	LY6/PLAUR domain containing 6B
chr12_-_68379331	0.725	NM_032735	BEST3	bestrophin 3
chr16_+_82885821	0.720	NM_021197	WFDC1	WAP four-disulfide core domain 1
chr4_+_111053488	0.712	NM_001178130 NM_001178131 NM_001963	EGF	epidermal growth factor
chr1_+_158352143	0.712	NM_000702	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr3_-_11585264	0.710	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chrX_-_138114846	0.708	NM_001139498 NM_001139500 NM_001139501	FGF13	fibroblast growth factor 13
chrX_-_142550535	0.691	NM_173078	SLITRK4	SLIT and NTRK-like family, member 4
chr12_-_242255	0.679	NM_001190997 NM_016615	SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr10_+_91082218	0.677	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr3_+_42702014	0.676	NM_152393	KBTBD5	kelch repeat and BTB (POZ) domain containing 5
chr11_-_62213946	0.664	NM_203422	LRRN4CL	LRRN4 C-terminal like
chr6_-_169395847	0.662		THBS2	thrombospondin 2
chr19_-_58086410	0.660	NM_207333	ZNF320	zinc finger protein 320
chr6_+_136214495	0.656	NM_018945	PDE7B	phosphodiesterase 7B
chr1_-_116112853	0.654		CASQ2	calsequestrin 2 (cardiac muscle)
chr17_-_31548167	0.649	NM_001001437 NM_021006	CCL3L3 CCL3 CCL3L1	chemokine (C-C motif) ligand 3-like 3 chemokine (C-C motif) ligand 3 chemokine (C-C motif) ligand 3-like 1
chr8_-_122722674	0.649	NM_005328	HAS2	hyaluronan synthase 2
chr1_-_116112921	0.648	NM_001232	CASQ2	calsequestrin 2 (cardiac muscle)
chr5_+_175041069	0.641	NM_022304	HRH2	histamine receptor H2
chr10_+_88418147	0.636	NM_001171610	LDB3	LIM domain binding 3
chr2_-_189752575	0.632	NM_000393	COL5A2	collagen, type V, alpha 2
chr6_-_169395972	0.631	NM_003247	THBS2	thrombospondin 2
chr2_+_219991342	0.630	NM_001927	DES	desmin
chr19_+_19872700	0.627	NM_031218	ZNF93	zinc finger protein 93
chr4_+_114190233	0.627	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr9_-_135379888	0.625	NM_001080483	TMEM8C	transmembrane protein 8C
chr3_-_69254226	0.622	NM_198271	LMOD3	leiomodin 3 (fetal)
chr19_+_43847049	0.620
chrX_-_138114817	0.619		FGF13	fibroblast growth factor 13
chr16_-_29797172	0.616		SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr4_-_1185144	0.615		LOC100130872	hypothetical LOC100130872
chr18_+_12397894	0.607	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr12_-_54522881	0.604	NM_002429	MMP19	matrix metallopeptidase 19
chr17_+_35075124	0.604	NM_003673	TCAP	titin-cap (telethonin)
chr1_+_144236398	0.603		ITGA10	integrin, alpha 10
chr19_-_55912006	0.602	NM_016148	SHANK1	SH3 and multiple ankyrin repeat domains 1
chr14_-_103058568	0.598		CKB	creatine kinase, brain
chr3_-_48573556	0.590		PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr4_+_120276386	0.583	NM_016599	MYOZ2	myozenin 2
chr1_+_144236346	0.582	NM_003637	ITGA10	integrin, alpha 10
chr5_-_83052606	0.579	NM_001884	HAPLN1	hyaluronan and proteoglycan link protein 1
chr5_+_176494690	0.578		NSD1	nuclear receptor binding SET domain protein 1
chr17_-_43254117	0.575		OSBPL7	oxysterol binding protein-like 7
chr1_-_31618405	0.562	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_+_146820805	0.558	NM_001080531	C4orf51	chromosome 4 open reading frame 51
chr2_+_5750229	0.552	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr15_+_66695932	0.544	NM_001190456	CORO2B	coronin, actin binding protein, 2B
chr8_+_1980564	0.544	NM_003970	MYOM2	myomesin (M-protein) 2, 165kDa
chr4_-_138673078	0.542	NM_019035	PCDH18	protocadherin 18
chr16_-_49205063	0.541
chr17_-_43254132	0.541	NM_145798	OSBPL7	oxysterol binding protein-like 7
chr4_+_41057322	0.539		LIMCH1	LIM and calponin homology domains 1
chr3_-_139317140	0.539	NM_173543	DZIP1L	DAZ interacting protein 1-like
chr19_+_3884100	0.535	NM_170678	ITGB1BP3	integrin beta 1 binding protein 3
chr10_-_14412813	0.530	NM_018027	FRMD4A	FERM domain containing 4A
chr2_+_220007943	0.530	NM_005876	SPEG	SPEG complex locus
chr9_+_138991775	0.518	NM_000954	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr3_+_139550134	0.518	NM_001085049	MRAS	muscle RAS oncogene homolog
chr5_+_132037271	0.516	NM_000589 NM_172348	IL4	interleukin 4
chr9_-_99740243	0.512	NM_197978	HEMGN	hemogen
chr4_+_41057507	0.506	NM_001112717 NM_001112718 NM_014988	LIMCH1	LIM and calponin homology domains 1
chr3_-_113842652	0.506	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr10_-_62373828	0.505	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr8_+_66744659	0.503	NM_001145838	MTFR1	mitochondrial fission regulator 1
chr1_-_149611768	0.501	NM_003944	SELENBP1	selenium binding protein 1
chr10_+_5478521	0.499	NM_005863	NET1	neuroepithelial cell transforming 1
chr7_-_76667045	0.498	NM_006682	FGL2	fibrinogen-like 2
chr5_+_140532385	0.498	NM_018940	PCDHB7	protocadherin beta 7
chrX_-_11194015	0.497	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr17_+_1612056	0.496		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_-_91395194	0.493	NM_148977	PANK1	pantothenate kinase 1
chr6_-_165643064	0.492	NM_144980	C6orf118	chromosome 6 open reading frame 118
chr3_+_185300660	0.490	NM_182589	HTR3E	5-hydroxytryptamine (serotonin) receptor 3, family member E
chr10_-_121592020	0.485		MCMBP	minichromosome maintenance complex binding protein
chr10_+_86174665	0.483		FAM190B	family with sequence similarity 190, member B
chr4_+_41057600	0.483
chr3_-_193928038	0.478	NM_004113	FGF12	fibroblast growth factor 12
chr17_-_10265991	0.476	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr1_-_115039614	0.474	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr4_-_186934059	0.472	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr6_-_131333173	0.468		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr9_+_130056513	0.467
chr1_+_144183811	0.460		ANKRD34A	ankyrin repeat domain 34A
chr3_-_171070314	0.459	NM_024727	LRRC31	leucine rich repeat containing 31
chr5_+_244625	0.458	NM_001080478	LRRC14B	leucine rich repeat containing 14B
chr19_+_12064077	0.457		ZNF788	zinc finger family member 788
chr14_+_99309688	0.454		EML1	echinoderm microtubule associated protein like 1
chr19_-_2207415	0.454	NM_144616	JSRP1	junctional sarcoplasmic reticulum protein 1
chr5_+_140730014	0.452	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr11_+_46339691	0.448	NM_001105540	DGKZ	diacylglycerol kinase, zeta
chr2_-_217268492	0.442	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr17_-_26672757	0.441	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr10_-_95231933	0.439	NM_013451 NM_133337	MYOF	myoferlin
chr22_-_28972683	0.435	NM_002309	LIF	leukemia inhibitory factor (cholinergic differentiation factor)
chr17_+_1612031	0.434		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_10362583	0.432	NM_005963	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr5_-_140875591	0.430		DIAPH1	diaphanous homolog 1 (Drosophila)
chr13_-_59223074	0.429
chr5_-_42847716	0.426	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr7_+_100037817	0.424	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr11_+_1897374	0.418	NM_001042780 NM_001042781 NM_001042782 NM_006757	TNNT3	troponin T type 3 (skeletal, fast)
chr1_+_25629968	0.418	NM_018202	TMEM57	transmembrane protein 57
chr17_+_1611983	0.418	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_+_70438352	0.417	NM_012278	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr1_-_156923111	0.417	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr3_+_50291521	0.416	NM_153215	C3orf45	chromosome 3 open reading frame 45
chr12_+_52696908	0.416	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr5_+_121493113	0.412	NM_207317	ZNF474	zinc finger protein 474
chr1_-_24311212	0.411	NM_152372	MYOM3	myomesin family, member 3
chr7_+_110518297	0.405	NM_001099658 NM_001099660 NM_018334	LRRN3	leucine rich repeat neuronal 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.62	6.65e-07	GO:0061061	muscle structure development
2.88	3.88e-06	GO:0007517	muscle organ development
2.77	7.95e-05	GO:0003012	muscle system process
2.31	2.17e-04	GO:0030029	actin filament-based process
4.77	3.01e-03	GO:0030049	muscle filament sliding
4.77	3.01e-03	GO:0033275	actin-myosin filament sliding
4.65	4.27e-03	GO:0070252	actin-mediated cell contraction
2.49	1.06e-02	GO:0006936	muscle contraction
3.73	3.19e-02	GO:0030048	actin filament-based movement
2.59	3.66e-02	GO:0042692	muscle cell differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.57	6.67e-14	GO:0030016	myofibril
4.31	6.29e-13	GO:0043292	contractile fiber
4.45	1.04e-12	GO:0044449	contractile fiber part
4.71	1.96e-12	GO:0030017	sarcomere
4.53	6.09e-05	GO:0031674	I band
4.65	6.28e-04	GO:0030018	Z disc

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.98	4.10e-03	GO:0003779	actin binding
1.71	9.25e-03	GO:0008092	cytoskeletal protein binding
3.79	2.52e-02	GO:0008307	structural constituent of muscle